Why is the sting of a scorpion more painful than that of a snake sting? What are the chemicals in their poisons?

Scorpion’s venom acts on the nerve tips and roots whereas snake’s poison acts on dendrites and axons of the nerves. As defence and prey capture are the sole aim of these and other animals and insects, it is the purpose on hand that determines venom’s composition and type.

 Cobra venom consists of 10 different enzymes, several different types of neurotoxins, cardio-toxins, cytotoxins, dendrotoxins and fasciculins (for example, lysocephalins, lysolecithins which are phospholipids). Snakes of the elapidae family (for example cobras, kraits and mambas) have venoms that kill primarily through neuro-muscular paralysis. It contains 60-75 amino acids and target nicotinic cholinoceptors in the muscle cell membranes which are sensitive to a chemical transmitter, acetylcholine. (Acetylcholine is released from nerve endings in response to an electrical impulse in the nerves.) The amino acids in snake’s venom block the junction between the nerves and the muscle. Scorpion’s venom consists of an arsenal of toxic compounds which contain 37 amino acids called charybdotoxin.

            When a scorpion stings these acids incapacitate the nerve cells causing severe pain, by rigidly binding with sulphur bonds unlike the snake’s toxin which binds by a ligand series. Moreover snake’s venom is digestible, but scorpion’s venom is not