Allergy is a state of hypersensitivity acquired through the exposure to a particular substance, called allergen. Spores, pollen, cat’s hair and proteins of egg, milk, and fish are some common allergens. The most common allergen is the house-dust mite.
Usually only parts of the body which are exposed to allergens show signs of allergy in the form of rashes or weals. However, if an allergen gets into the blood stream, it can cause reactions almost anywhere in the body.
Practically all allergies are caused by an over-reaction of the body’s defence mechanism when white blood cells react with allergens considering them as dangerous infectious organisms, it leads to allergy. Under normal conditions, the white blood cells (lymphocytes) on coming in contact with foreign substances like bacteria, viruses and proteinaceous matter produce what are called antibodies. The antibodies combine with the foreign substance and neutralize it. But when an antibody is formed against a harmless protein it attaches itself to mast cells which contain chemical— histamine. When the particular protein enters the body again, histamine is released. Due to the action of histamine blood capillaries are dilated, their walls become leaky and fluid from the blood comes out in the nearby tissues and they swell. The characteristic redness and itching in an allergy is due to dilation of blood capillaries.
