What differentiates humans from animals?

Biologists classify humans as animals and part of the animal kingdom. Like our nearest relatives, the apes, humans are also mammals. Humans have evolved from apes, but there are features that differentiate us from other animals—including apes. These include the upright walk, our opposable thumb, our special ability to communicate by a language, and our highly developed brain. Our brain allowed our ancestors, like the Neanderthals, to invent tools.